— BODY & WELLNESS —
NAD+ Therapy
A coenzyme found in every cell, central to cellular energy — offered as a quick injection, with infusion options available by consultation.
Administered by licensed medical providers · Physician Supervised
At a glance
- Injection, 100 mg$150
- Infusion, 250 mg$400
- Visit length
- A few minutes for the injection. IV infusions run about 90 minutes at 250 mg and about 180 minutes at 500 mg, paced for comfort.
— Treatment Overview —
About NAD+ at Chicago Medspa
NAD+ is a coenzyme found in every cell, central to cellular energy. We offer NAD+ as a quick injection, with infusion options available by consultation. Every NAD+ plan starts with a complimentary consultation with our clinical team. Performed under physician supervision.
— Choosing a Format —
The Injection and the Infusion Are Different Appointments
The injection is the shorter of the two. It is given intramuscularly or subcutaneously at 100 mg, takes minutes, and sits alongside the rest of our wellness injections as a short visit rather than an infusion appointment. It carries a lower side-effect burden than the drip, and what side effects it does carry are dose-dependent, becoming more common above roughly 200 to 300 mg.
The infusion is a longer commitment and is booked as IV therapy. A 250 mg infusion runs about ninety minutes. A 500 mg infusion runs about three hours. The difference is not only the dose but the pace, because NAD+ is infused slowly on purpose. It can also be added to another infusion as a booster rather than booked on its own, which is one of the options on our IV add-ons list.
Which format suits you is a conversation rather than a preference. Your provider sets the format, the dose and the cadence with you at consultation.
— The Experience —
Why the Drip Rate Matters
NAD+ infusions are started slowly and titrated to tolerance, commonly beginning around 125 mL per hour. That pacing is the point of the appointment length rather than an inconvenience within it.
NAD+ activates a receptor associated with the familiar niacin flush, which causes vasodilation. Where an infusion runs too quickly, that can present as flushing, warmth, nausea, abdominal cramping, a sensation of chest tightness or pressure, or palpitations. All of it is mitigated by slowing the drip, which is exactly what your provider does when it appears. This is why the infusion is attended rather than left running, and why you are monitored for at least fifteen minutes.
Some symptoms are not managed by slowing down. Chest pain, difficulty breathing, swelling of the face or throat, or faintness stop the infusion and are evaluated urgently. Your provider will tell you what to say and when to say it before the line is started.
— Candidacy —
Who NAD+ Therapy Is Not For
Every first infusion at Chicago Medspa is preceded by a good-faith examination: history and physical with a licensed provider, review of renal function because of the fluid and electrolyte load, review of cardiac status, an allergy history, and a full medication review. Pregnancy and breastfeeding are handled as a physician decision rather than a protocol, because safety in those groups is not established.
NAD+ specifically calls for caution in cardiac disease and in pregnancy. It interacts with several medication classes, including diabetes medications, antihypertensives, blood thinners and antidepressants. None of that is a checklist you complete alone. It is the reason the consultation exists, and it is why the consultation is complimentary and carries no obligation to book.
— Evidence —
What the Evidence Currently Supports
We would rather set this expectation ourselves than let you find it elsewhere. Human evidence for intravenous NAD+ is limited. It rests largely on a single open-label pilot study of eleven participants, published in Frontiers in Aging Neuroscience in 2019, in which 750 mg was infused over six hours specifically to avoid adverse events. That study measured plasma NAD+ rising over the course of the infusion. It was not designed to establish clinical outcomes, and it has not been replicated at scale.
More broadly, high-dose intravenous vitamin and cofactor therapy is an area where the Merck Manual notes that claims lack supporting data and that the field lacks regulatory oversight. We publish that here on purpose. NAD+ therapy is offered as a wellness service under physician supervision, not as a treatment for any condition, and your provider will frame what it can and cannot be expected to do before you decide.
— Planning Your Visit —
Treatment Details
Pricing
- Injection, 100 mg$150
- Infusion, 250 mg$400
- Infusion, 500 mg$650
The injection is a short visit and the infusions are longer appointments. These are the prices in our online booking. Your plan is confirmed at the complimentary consultation, with no obligation to book.
- Appointment Length
- A few minutes for the injection. IV infusions run about 90 minutes at 250 mg and about 180 minutes at 500 mg, paced for comfort.
Format, dose, and cadence are set with your provider at consultation.
No deposit, no fees
Your consultation is complimentary, with no obligation to book. We take no deposit to hold your appointment, and we charge nothing to cancel, to reschedule, or for a visit you miss.
— Frequently Asked —
Questions, Answered
How do I begin?
Is NAD+ offered as an injection or an infusion?
Who oversees NAD+ therapy?
Why does the infusion take so long?
What should I say if I feel unwell during the infusion?
Is there anyone NAD+ is not suitable for?
What does the evidence actually show?
— Explore Next —
Related Treatments
— Begin Here —
Start with a Professional Consultation
Your consultation is complimentary, with no obligation to book.
Compounded medications are prepared for individual patients by a licensed compounding pharmacy based on a prescription following consultation. Compounded medications are not FDA-approved.